Postdoctoral fellow bioinformatics– single-cell sequencing …, Amsterdam

About

your

role

You will work at the interface of computational method development, pipeline engineering, and translational cancer research, with a focus on understanding therapy resistance in acute myeloid leukemia (AML). Your tasks include: developing, optimizing, and maintaining reproducible computational pipelines for single-cell long-read data (e.g. improving or extending tools such as FLAMES or related frameworks);designing analytical strategies to genotype individual cells and study clonal dynamics in longitudinal AML samples; integrating single-cell multi-omics datasets, including scRNA-seq, scATAC-seq and CITE-seq to study mechanisms of therapy resistance; ensuring pipelines are robust, well-documented, and accessible for other researchers;translating complex datasets into biological insights in collaboration with experimental scientists.

About

you

You are a computational scientist with a strong interest in biology and enjoy working in a collaborative research environment. You combine technical expertise with analytical thinking and clear communication. You bring: a PhD (or near completion) in bioinformatics, computational biology, computer science, statistics, or a related field;strong programming skills in Python and/or R; experience with single-cell genomics data analysis, such as scRNA-seq, scATAC-seq or multiome data; experience with workflow management systems (e.g. Nextflow, Snakemake or WDL) and version control (Git); strong communication, presentation, and scientific writing skills, and the ability to work both independently and collaboratively.Experience with long-read sequencing, isoform analysis, variant calling, or scalable computing environments is considered an advantage.

Our offer

A flying start to your career in scientific research. Plenty of room for your drive to shape tomorrow's healthcare. Working on large-scale and in-house research, with motivated colleagues from all over the world. You will be employed by Amsterdam UMC Research BV. A contract for 12 months, with the intention to extend for the duration of the project.Salary scale 10:€ 3.598 tot € 5.669 gross based on full-time employment (depending on education and experience) and a year-end bonus of 8.3%. Holiday hours: 190,4 per year for fulltime and a possibility to save additional hours. Pension accrual with BeFrank, a modern, comprehensible and fairly priced pension.100% reimbursement for public transport travel costs. If you travel by foot, bicycle, or car, a mileage allowance of€0.21 per km applies (up to a maximum of 40 km one way by car).

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