Researcher in Training (PhD Candidate), Leiden
Researcher in Training (PhD Candidate), Leiden
-
2300 Leiden, Nederland -
Geplaatst op: minder dan een week geleden
-
Onthouden -
Delen
Advertentietekst
Overview Within a multidisciplinary team of neurologists, immunologists and bioinformaticians, you will work on an integrated research programme combining computational analyses and laboratory experiments. In the first part of the project, you will analyse large‑scale human transcriptomic datasets to identify genes specifically expressed in hypocretin‑producing neurons. The next phase will use structural modelling to investigate protein fragments that may bind strongly to the HLA molecule associated with narcolepsy. In the experimental phase, you willtest the most promising candidates using T‑cell assays, flow cytometry and functional immune assays, covering the entire research cycle from experimental design to publication.
Key Responsibilities
Analysing large‑scale transcriptomic datasets and identifying candidate targets for narcolepsy research.
Investigating protein‑HLA interactions using structural modelling, AI methods and molecular simulations.
Setting up and performing T‑cell assays and immunological experiments using patient material from the Narcolepsy Biobank.
Presenting research findings at national and international conferences and writing scientific publications as part of your PhD thesis.
Qualifications
A master’s degree in Biomedical Sciences, Immunology, Neuroscience or a related field, with demonstrated affinity for immunology and neuroscience.
Interest in both computational and experimental techniques.
Willingness to learn new techniques, such as molecular modelling.
Strong communication skills in English; Dutch is a plus, but not required.
Experience with RNA‑seq analysis, Python/R, molecular modelling, immunological assays or flow cytometry is an advantage.
Benefits
End‑of‑year bonus of 8.3 %.
Holiday allowance, bicycle scheme, sports budget and home‑working allowance.
Excellent commuting reimbursement scheme.
Affiliation with the ABP pension fund with at least 70 % of contribution paid by LUMC.
Employment Details
Salary ranges from€3,108 to €3,939 gross per month (scale PRO, Collective Labour Agreement for University Medical Centres) for a full‑time position.
Four‑year PhD trajectory with an intended start date in mid‑2026.
Appointment is for 36 hours per week; 0.9–1.0 FTE open for discussion.
#J-18808-Ljbffr
Key Responsibilities
Analysing large‑scale transcriptomic datasets and identifying candidate targets for narcolepsy research.
Investigating protein‑HLA interactions using structural modelling, AI methods and molecular simulations.
Setting up and performing T‑cell assays and immunological experiments using patient material from the Narcolepsy Biobank.
Presenting research findings at national and international conferences and writing scientific publications as part of your PhD thesis.
Qualifications
A master’s degree in Biomedical Sciences, Immunology, Neuroscience or a related field, with demonstrated affinity for immunology and neuroscience.
Interest in both computational and experimental techniques.
Willingness to learn new techniques, such as molecular modelling.
Strong communication skills in English; Dutch is a plus, but not required.
Experience with RNA‑seq analysis, Python/R, molecular modelling, immunological assays or flow cytometry is an advantage.
Benefits
End‑of‑year bonus of 8.3 %.
Holiday allowance, bicycle scheme, sports budget and home‑working allowance.
Excellent commuting reimbursement scheme.
Affiliation with the ABP pension fund with at least 70 % of contribution paid by LUMC.
Employment Details
Salary ranges from€3,108 to €3,939 gross per month (scale PRO, Collective Labour Agreement for University Medical Centres) for a full‑time position.
Four‑year PhD trajectory with an intended start date in mid‑2026.
Appointment is for 36 hours per week; 0.9–1.0 FTE open for discussion.
#J-18808-Ljbffr
Belangrijke informatie
-
BedrijfsnaamLeiden University Medical Center -
PositieResearcher in Training (PhD Candidate)
-
Melden -
Advertentie blokkeren
Veiligheidstips
Vertrouw je gevoel: als het te mooi om waar te zijn lijkt, is het dat meestal ook.
Gerelateerde zoekopdrachten
Meer informatie over deze advertentie
Researcher in Training (PhD Candidate) is geplaatst in de Leiden toerisme, reizen, hotels rubriek op Locanto.
Voor Leiden zijn er geen andere advertenties in deze rubriek.
Geïnteresseerd in meer? Verbreed je zoekopdracht om advertenties in nabijgelegen gebieden van Leiden. te bekijken. Dit omvat toerisme, reizen, hotels in Wassenaar, Teijlingen en Alphen aan den Rijn. In totaal zijn er 7 advertenties binnen een straal van 15 km voor deze rubriek. Als je deze advertenties wilt bekijken, klikt u hier.
